Letters to the Editor
23 September 2009
Vol. 53 No. 3 (2009)
https://doi.org/10.4081/ejh.2009.e22
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Niemann-Pick disease, type B with TRAP-positive storage cells and secondary sea blue histiocytosis

Authors

P. Sharma
prashant.sh@gmail.com
R. Kar
S. Dutta
H.P. Pati
R. Saxena
We present 2 cases of Niemann Pick disease, type B with secondary sea-blue histiocytosis. Strikingly, in both cases the Pick cells were positive for tartrate resistant acid phosphatase, a finding hitherto described only in Gaucher cells. This report highlights the importance of this finding as a potential cytochemical diagnostic pitfall in the diagnosis of Niemann Pick disease.

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Niemann-Pick disease, type B with TRAP-positive storage cells and secondary sea blue histiocytosis. (2009). European Journal of Histochemistry, 53(3), e22. https://doi.org/10.4081/ejh.2009.e22

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