Stem Cells & Regenerative Medicine - From molecular embryology to tissue engineering

Submitted: 5 April 2011
Accepted: 5 April 2011
Published: 15 September 2011
Abstract Views: 751
PDF: 371
HTML: 246
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Authors

Maria J. Barrero and Juan Carlos Izpisua Belmonte sign a very interesting paper on EMBO reports (Regenerating the epigenome, EMBO reports 12:208-215, 2011) where they point out that Organisms have evolved two strategies by which to achieve this: the maintenance of adult stem cells and the induction of stemcell properties in differentiated cells. In both cases, cells must undergo extensive epigenetic reprogramming to attain the specialized functions of the new tissue. Ultimately, the regenerative capacity of a tissue might depend on the plasticity of the cellular epigenome, which determines the ability of the cell to respond to injuryrelated signals. Understanding this epigenetic plasticity will allow the development of strategies to stimulate the regeneration of damaged tissues and organs in humans...

Dimensions

Altmetric

PlumX Metrics

Downloads

Download data is not yet available.

Citations

How to Cite

Redi, C. A. (2011). Stem Cells & Regenerative Medicine - From molecular embryology to tissue engineering. European Journal of Histochemistry, 55(3), br8. https://doi.org/10.4081/ejh.2011.br8