https://doi.org/10.4081/ejh.2011.e24

Immunohistochemical expression of types I and III collagen antibodies in the temporomandibular joint disc of human foetuses

Vol. 55 No. 3 (2011)
Submitted: 7 February 2011
Accepted: 24 May 2011
Published: 21 July 2011
articular disc, temporomandibular joint, human foetuses, collagen, immunohistochemical, embryology
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Authors

L.O.C. de Moraes
luisotavio27@yahoo.com.br
Universidade Federal de São Paulo, Brazil.
F.R. Lodi
Universidade Federal de São Paulo, Brazil.
T. S. Gomes
Universidade Federal de São Paulo, Brazil.
C.T.F. Oshima
Universidade Federal de São Paulo, Brazil.
S.R. Marques
Universidade Federal de São Paulo, Brazil.
C.L.P. Lancellotti
Santa Casa de São Paulo, Brazil.
J.F. Rodriguez-Vázquez
Universidad Complutense de Madrid, Spain.
J.R. Mérida-Velasco
Universidad Complutense de Madrid, Spain.
L.G. Alonso
Universidade Federal de São Paulo, Brazil.
The objective was to study the morphology of the articular disc and analyse the immunohistochemical expression of types I and III collagen markers in the temporomandibular joint (TMJ) disc of human foetuses of different gestational ages. Twenty TMJ from human foetuses supplied by Universidade Federal de Uberaba with gestational ages from 17 to 24 weeks were studied. The gestational age of the foetuses was determined by measuring the crown-rump (CR) length. Macroscopically, the foetuses were fixed in 10% formalin solution and dissected by removing the skin and subcutaneous tissue and exposing the deep structures. Immunohistochemical markers of type I and III were used to characterize the existence of collagen fibres. Analysis of the immunohistochemical markers of types I and III collagen revealed the presence of heterotypical fibril networks.

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Europe PMC
L.O.C. de Moraes, Universidade Federal de São Paulo
Departamento de Morfologia e Genética
F.R. Lodi, Universidade Federal de São Paulo
Departamento de Morfologia e Genética
S.R. Marques, Universidade Federal de São Paulo
Departamento de Morfologia e Genética
C.L.P. Lancellotti, Santa Casa de São Paulo
Departamento de Ciências Patológicas
J.F. Rodriguez-Vázquez, Universidad Complutense de Madrid
Departamento de Anatomía y Embriología II
J.R. Mérida-Velasco, Universidad Complutense de Madrid
Departamento de Anatomía y Embriología II
L.G. Alonso, Universidade Federal de São Paulo
Departamento de Morfologia e Genética

How to Cite

de Moraes, L., Lodi, F., Gomes, T. S., Oshima, C., Marques, S., Lancellotti, C., Rodriguez-Vázquez, J., Mérida-Velasco, J., & Alonso, L. (2011). Immunohistochemical expression of types I and III collagen antibodies in the temporomandibular joint disc of human foetuses. European Journal of Histochemistry, 55(3), e24. https://doi.org/10.4081/ejh.2011.e24

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