https://doi.org/10.4081/ejh.2016.2724
High temperature requirement A1 and fibronectin: two possible players in placental tissue remodelling
Submitted: 13 September 2016
Accepted: 9 November 2016
Published: 21 November 2016
Accepted: 9 November 2016
Abstract Views: 1124
PDF: 490
HTML: 145
HTML: 145
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
High temperature requirement A1 (HtrA1) is a secreted protease involved in placental development. Fibronectin (FN) is involved in important process such as wound healing, cell adhesion and spreading, growth, migration, and differentiation. The purpose of this study was to analyse the expression patterns of HtrA1 in relationship to FN and to the key growth zones of placenta such as mesenchymal villi as well as cell islands and cell columns. We demonstrated that FN and HtrA1 are localized in the placental key growth zones suggesting a pivotal role in maintaining the balance among the molecules involved in the placental development and differentiation.
Supporting Agencies
Italian Ministry and Research and Instruction, grant PRIN 2010-2011,How to Cite
Tossetta, G., Avellini, C., Licini, C., Giannubilo, S., Castellucci, M., & Marzioni, D. (2016). High temperature requirement A1 and fibronectin: two possible players in placental tissue remodelling. European Journal of Histochemistry, 60(4). https://doi.org/10.4081/ejh.2016.2724
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Similar Articles
- G. Goteri, E. Altobelli, G. Tossetta, A. Zizzi, C. Avellini, C. Licini, T. Lorenzi, M. Castellucci, A. Ciavattini, D. Marzioni, High temperature requirement A1, transforming growth factor beta1, phosphoSmad2 and Ki67 in eutopic and ectopic endometrium of women with endometriosis , European Journal of Histochemistry: Vol. 59 No. 4 (2015)
- A. Santoro, G. Pannone, M.E. Errico, D. Bifano, G. Lastilla, P. Bufo, C. Loreto, V. Donofrio, Role of β-catenin expression in paediatric mesenchymal lesions: a tissue microarray-based immunohistochemical study , European Journal of Histochemistry: Vol. 56 No. 3 (2012)
- D. Fanni, N. Iacovidou, A. Locci, C. Gerosa, S. Nemolato, P. Van Eyken, G. Monga, S. Mellou, G. Faa, V. Fanos, MUC1 marks collecting tubules, renal vesicles, comma- and S-shaped bodies in human developing kidney , European Journal of Histochemistry: Vol. 56 No. 4 (2012)
- S. Shibata, H. Fukuoka, R. Sato, T. Abe, Y. Suzuki, An in situ hybridization study of the insulin-like growth factor system in developing condylar cartilage of the fetal mouse mandible , European Journal of Histochemistry: Vol. 56 No. 2 (2012)
- M. Artico, E. Bronzetti, B. Ionta, M. Bruno, A. Greco, G. Ruoppolo, A. De Virgilio, L. Longo, M. De Vincentiis, Reinke's Edema: investigations on the role of MIB-1 and hepatocyte growth factor , European Journal of Histochemistry: Vol. 54 No. 3 (2010)
- Damián Sánchez-Ramírez, Rafael Medrano-Guzmán, Fernando Candanedo-González, Jazmín De Anda-González, Luis Enrique García-Rios, Vadim Pérez-Koldenkova, Marcos Gutiérrez-de la Barrera, Sara Rodríguez-Enríquez, Marco Velasco-Velázquez, Silvia Cecilia Pacheco-Velázquez, Patricia Piña-Sánchez, Héctor Mayani, Alejandro Gómez-Delgado, Alberto Monroy-García, Ana Karen Martínez-Lara, Juan José Montesinos, High expression of both desmoplastic stroma and epithelial to mesenchymal transition markers associate with shorter survival in pancreatic ductal adenocarcinoma , European Journal of Histochemistry: Vol. 66 No. 1 (2022)
- S. San Martin, J. Fitzgerald, M. Weber, M. Párraga, T. Sáez, T.M. Zorn, U.R. Markert, STAT3 and SOCS3 expression patterns during murine placenta development , European Journal of Histochemistry: Vol. 57 No. 2 (2013)
- L. M. Carrillo, E. Arciniegas, H. R. Rojas, R. E. Ramirez, Immunolocalization of endocan during the endothelial-mesenchymal transition process , European Journal of Histochemistry: Vol. 55 No. 2 (2011)
- Yuuki Maeda, Yoko Miwa, Iwao Sato, Expression of CGRP, vasculogenesis and osteogenesis associated mRNAs in the developing mouse mandible and tibia , European Journal of Histochemistry: Vol. 61 No. 1 (2017)
- R. Pennati, A. Dell'Anna, G. Zega, F. De Bernardi, Immunohistochemical study of the nervous system of the tunicate Thalia democratica (Forsskal, 1775) , European Journal of Histochemistry: Vol. 56 No. 2 (2012)
You may also start an advanced similarity search for this article.
Publication Facts
Metric
This article
Other articles
Peer reviewers
1
2.4
Reviewer profiles N/A
Author statements
Author statements
This article
Other articles
Data availability
N/A
16%
External funding
N/A
32%
Competing interests
N/A
11%
Metric
This journal
Other journals
Articles accepted
57%
33%
Days to publication
68
145
- Editor & editorial board
- profiles
- Academic society
- N/A
- Publisher
- PAGEPress Publications, Pavia, Italy
To learn about these publication facts, click 
PF is maintained by the Public Knowledge Project
