https://doi.org/10.4081/1683
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PACAP activated adenylate cyclase in human sweat glands. An ultracytochemical study

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MG Rambotti
support@pagepress.org
PAGEPress Office, Pavia, Italy.
S Simonetti
A Spreca
The ultracytochemical localization of adenylate cyclase (AC) was studied after stimulation with pituitary adenylate cyclase activating peptide (PACAP) in human sweat glands. PACAP stimulated AC in both eccrine and apocrine glands. In the secretory cells, enzymatic activity was associated with membranes involved in the secretory mechanism. In both glands, the cells of the excretory duct and myoepithelial cells presented AC activity. These localizations of enzymatic activity suggest a role for PACAP in regulating glandular secretion.

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PACAP activated adenylate cyclase in human sweat glands. An ultracytochemical study. (2010). European Journal of Histochemistry, 46(3), 223-8. https://doi.org/10.4081/1683

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