https://doi.org/10.4081/ejh.2015.2569
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Development of synovial membrane in the temporomandibular joint of the human fetus

Authors

L.O. Carvalho de Moraes
luisotavio27@yahoo.com.br
Federal University of São Paulo, Brazil.
R.C. Tedesco
Federal University of São Paulo, Brazil.
L.A. Arraez-Aybar
University Complutense of Madrid, Spain.
O. Klein
University of California, San Francisco, United States.
J.R. Mérida-Velasco
University Complutense of Madrid, Spain.
L.G. Alonso
Federal University of São Paulo, Brazil.
The development of the synovial membrane was analyzed in serial sections of 21 temporomandibular joints of human fetuses at 9 to 13 weeks of gestation. Sections of two fetuses at 12 weeks of development were used to perform immunohistochemical expression of the markers CD68 and Hsp27 on the synovial lining. Macrophage-like type A and fibroblast-like type B cells, which express CD68 and Hsp27, respectively, were observed at the twelfth week of development. Our results suggest that the development of the synovial membrane is related to the vascularization of the joint and the formation of the articular cavities.

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Supporting Agencies

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
L.O. Carvalho de Moraes, Federal University of São Paulo
Department of Morphology and Genetics
R.C. Tedesco, Federal University of São Paulo
Department of Morphology and Genetics
L.A. Arraez-Aybar, University Complutense of Madrid
Department of Anatomy and Embryology
O. Klein, University of California, San Francisco
Department of Orofacial Sciences and Program in Craniofacial and Mesenchymal Biology
J.R. Mérida-Velasco, University Complutense of Madrid
Department of Anatomy and Embryology
L.G. Alonso, Federal University of São Paulo
Department of Morphology and Genetics

How to Cite

Carvalho de Moraes, L., Tedesco, R., Arraez-Aybar, L., Klein, O., Mérida-Velasco, J., & Alonso, L. (2015). Development of synovial membrane in the temporomandibular joint of the human fetus. European Journal of Histochemistry, 59(4). https://doi.org/10.4081/ejh.2015.2569

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