https://doi.org/10.4081/ejh.2017.2851
DNA damage in acute myeloid leukemia patients of Northern Mexico
Submitted: 14 September 2017
Accepted: 30 November 2017
Published: 11 December 2017
Accepted: 30 November 2017
Abstract Views: 1030
PDF: 450
HTML: 129
HTML: 129
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
The purpose of this study was to evaluate DNA damage in the whole genome of peripheral blood leukocytes from patients with acute myeloid leukemia (AML) compared with a control group using DNA breakage detection-fluorescent in situ hybridization (DBD-FISH). Our results suggest that the DNA damage detected in patients with newly diagnosed AML was similar to that observed for the controls; this might be explained by the stimulation of a repair pathway by the pathogenesis itself. These findings indicate that inhibiting the repair pathway could be proposed to enhance the efficacy of chemotherapy.
Supporting Agencies
Instituto Mexicano del Seguro Social, CONACYT.How to Cite
Dávila-Rodríguez, M. I., Cortés-Gutiérrez, E. I., Hernández-Valdés, R., Guzmán-Cortés, K., De León-Cantú, R. E., Cerda-Flores, R. M., & Báez-De la Fuente, E. (2017). DNA damage in acute myeloid leukemia patients of Northern Mexico. European Journal of Histochemistry, 61(4). https://doi.org/10.4081/ejh.2017.2851
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Similar Articles
- Feng Chen, Wenfeng Li, Dandan Zhang, Youlin Fu, Wenjin Yuan, Gang Luo, Fuwei Liu, Jun Luo, MALAT1 regulates hypertrophy of cardiomyocytes by modulating the miR-181a/HMGB2 pathway , European Journal of Histochemistry: Vol. 66 No. 3 (2022)
- Matias Garrido, Camila Escobar, Constanza Zamora, Carolina Rejas, Juan Varas, Mario Párraga, Sebastián San Martin, Sandra Montedonico, Bile duct ligature in young rats: A revisited animal model for biliary atresia , European Journal of Histochemistry: Vol. 61 No. 3 (2017)
- Lucia Aidos, Luisa M. Pinheiro Valente, Vera Sousa, Marco Lanfranchi, Cinzia Domeneghini, Alessia Di Giancamillo, Effects of different rearing temperatures on muscle development and stress response in the early larval stages of Acipenser baerii , European Journal of Histochemistry: Vol. 61 No. 4 (2017)
- Claudia Lombardo, Grazia Maugeri, Agata Grazia D'Amico, Giuseppe Broggi, Rosario Caltabiano, Veronica Filetti, Serena Matera, Velia D'Agata, Carla Loreto, Pleural mesothelioma from fluoro-edenite exposure: PACAP and PAC1 receptor. A preliminary report , European Journal of Histochemistry: Vol. 68 No. 2 (2024)
- M. A. Sandhu, A. A. Saeed, M. S. Khilji, R. H. Pasha, N. Mukhtar, M. S. Anjum, Ontogenic development of corticotrophs in fetal buffalo (Bubalus bubalis) pituitary gland , European Journal of Histochemistry: Vol. 58 No. 1 (2014)
- M Rosety, FJ Ordoñez, A Ribelles, M Rosety-Rodriguez, A Dominguez, C Carrasco, JM Rosety, Morpho-histochemical changes in the liver and intestine of young giltheads (fish-nursery), Sparus aurata, L., induced by acute action of the anionic tensioactive alkylbenzene sulphonate , European Journal of Histochemistry: Vol. 45 No. 3 (2001)
- Kazuhiko Hashimoto, Shunji Nishimura, Tomohiko Ito, Naohiro Oka, Ryosuke Kakinoki, Masao Akagi, Clinicopathological assessment of cancer/testis antigens NY‑ESO‑1 and MAGE‑A4 in osteosarcoma , European Journal of Histochemistry: Vol. 66 No. 3 (2022)
- M Nieddu, G Pichiri, S Manconi, R Mezzanotte, Some remarks on the use of TaqI to detect highly repetitive DNA sequences in human chromosomes , European Journal of Histochemistry: Vol. 50 No. 4 (2006)
- C. Pellicciari, M. Malatesta, Identifying pathological biomarkers: histochemistry still ranks high in the omics era , European Journal of Histochemistry: Vol. 55 No. 4 (2011)
- Yuhan Wang, Gang Wang, Xiaojun Liu, Dong Yun, Qing Cui, Xiaoting Wu, Wenfeng Lu, Xiwen Yang, Ming Zhang, Inhibition of APLN suppresses cell proliferation and migration and promotes cell apoptosis in esophageal cancer cells in vitro, through activating PI3K/mTOR signaling pathway , European Journal of Histochemistry: Vol. 66 No. 3 (2022)
<< < 36 37 38 39 40 41 42 43 44 45 > >>
You may also start an advanced similarity search for this article.
