https://doi.org/10.4081/ejh.2017.2851
DNA damage in acute myeloid leukemia patients of Northern Mexico
Accepted: 30 November 2017
HTML: 129
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
The purpose of this study was to evaluate DNA damage in the whole genome of peripheral blood leukocytes from patients with acute myeloid leukemia (AML) compared with a control group using DNA breakage detection-fluorescent in situ hybridization (DBD-FISH). Our results suggest that the DNA damage detected in patients with newly diagnosed AML was similar to that observed for the controls; this might be explained by the stimulation of a repair pathway by the pathogenesis itself. These findings indicate that inhibiting the repair pathway could be proposed to enhance the efficacy of chemotherapy.
Supporting Agencies
Instituto Mexicano del Seguro Social, CONACYT.How to Cite
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Similar Articles
- K Hirai, M Kumakiri, K Ueda, Y Imamura, S Noriki, Y Nishi, H Kato, M Fukuda, Clonal evolution and progression of 20-methylcholanthrene-induced squamous cell carcinoma of mouse epidermis as revealed by DNA instability and other malignancy markers , European Journal of Histochemistry: Vol. 45 No. 4 (2001)
- G. Natale, E. Pompili, F. Biagioni, S. Paparelli, P. Lenzi, F. Fornai, Histochemical approaches to assess cell-to-cell transmission of misfolded proteins in neurodegenerative diseases , European Journal of Histochemistry: Vol. 57 No. 1 (2013)
- I. Kopera, M. Durlej, A. Hejmej, K. Knapczyk-Stwora, M. Duda, M. Slomczynska, M. Koziorowski, B. Bilinska, Effects of pre- and postnatal exposure to flutamide on connexin 43 expression in testes and ovaries of prepubertal pigs , European Journal of Histochemistry: Vol. 54 No. 2 (2010)
- G Lingua, G D’Agostino, A Fusconi, G Berta, Nuclear changes in pathogen-infected tomato roots , European Journal of Histochemistry: Vol. 45 No. 1 (2001)
- C Soldani, MG Bottone, AC Croce, A Fraschini, G Bottiroli, C Pellicciari, The Golgi apparatus is a primary site of intracellular damage after photosensitization with Rose Bengal acetate , European Journal of Histochemistry: Vol. 48 No. 4 (2004)
- G. Lepore, S. Gadau, A. Mura, M. Zedda, V. Farina, Aromatase immunoreactivity in fetal ovine neuronal cell cultures exposed to oxidative injury , European Journal of Histochemistry: Vol. 53 No. 4 (2009)
- E Bonanno, G Tagliafierro, EC Carlà, MR Montinari, P Pagliara, G Mascetti, LG Spagnoli, L Dini, Synchronized onset of nuclear and cell surface modifications in U937 cells during apoptosis , European Journal of Histochemistry: Vol. 46 No. 1 (2002)
- V. Pibiri, A. Ravarino, C. Gerosa, M.C. Pintus, V. Fanos, G. Faa, Stem/progenitor cells in the developing human cerebellum: an immunohistochemical study , European Journal of Histochemistry: Vol. 60 No. 3 (2016)
- P. Demurtas, M. Corrias, I. Zucca, C. Maxia, F. Piras, P. Sirigu, M.T. Perra, Angiotensin II: immunohistochemical study in Sardinian pterygium , European Journal of Histochemistry: Vol. 58 No. 3 (2014)
- Simone Carotti, Giuseppe Perrone, Michelina Amato, Umberto Vespasiani Gentilucci, Daniela Righi, Maria Francesconi, Claudio Pellegrini, Francesca Zalfa, Maria Zingariello, Antonio Picardi, Andrea Onetti Muda, Sergio Morini, Reelin expression in human liver of patients with chronic hepatitis C infection , European Journal of Histochemistry: Vol. 61 No. 1 (2017)
<< < 38 39 40 41 42 43 44 45 46 47 > >>
You may also start an advanced similarity search for this article.
