https://doi.org/10.4081/ejh.2017.2851
DNA damage in acute myeloid leukemia patients of Northern Mexico
Submitted: 14 September 2017
Accepted: 30 November 2017
Published: 11 December 2017
Accepted: 30 November 2017
Abstract Views: 1030
PDF: 450
HTML: 129
HTML: 129
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
The purpose of this study was to evaluate DNA damage in the whole genome of peripheral blood leukocytes from patients with acute myeloid leukemia (AML) compared with a control group using DNA breakage detection-fluorescent in situ hybridization (DBD-FISH). Our results suggest that the DNA damage detected in patients with newly diagnosed AML was similar to that observed for the controls; this might be explained by the stimulation of a repair pathway by the pathogenesis itself. These findings indicate that inhibiting the repair pathway could be proposed to enhance the efficacy of chemotherapy.
Supporting Agencies
Instituto Mexicano del Seguro Social, CONACYT.How to Cite
Dávila-Rodríguez, M. I., Cortés-Gutiérrez, E. I., Hernández-Valdés, R., Guzmán-Cortés, K., De León-Cantú, R. E., Cerda-Flores, R. M., & Báez-De la Fuente, E. (2017). DNA damage in acute myeloid leukemia patients of Northern Mexico. European Journal of Histochemistry, 61(4). https://doi.org/10.4081/ejh.2017.2851
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Similar Articles
- R Acevedo, A Cuadrado, C De la Torre, S Moreno Díaz de la Espina, Behaviour of ribosomal genes and nucleolar domains during activation in sugarcane (Saccharum officinarum L.) root primordia: from the unsoaked quiescent state to the steady state of proliferation , European Journal of Histochemistry: Vol. 46 No. 2 (2002)
- Y. Asara, J. A. Marchal, P. Bandiera, V. Mazzarello, L. G. Delogu, M. A. Sotgiu, A. Montella, R. Madeddu, Cadmium influences the 5-Fluorouracil cytotoxic effects on breast cancer cells , European Journal of Histochemistry: Vol. 56 No. 1 (2012)
- Elena Pompili, Viviana Ciraci, Stefano Leone, Valerio De Franchis, Pietro Familiari, Roberto Matassa, Giuseppe Familiari, Ada Maria Tata, Lorenzo Fumagalli, Cinzia Fabrizi, Thrombin regulates the ability of Schwann cells to support neuritogenesis and to maintain the integrity of the nodes of Ranvier , European Journal of Histochemistry: Vol. 64 No. 2 (2020)
- A. Santoro, G. Pannone, M.E. Errico, D. Bifano, G. Lastilla, P. Bufo, C. Loreto, V. Donofrio, Role of β-catenin expression in paediatric mesenchymal lesions: a tissue microarray-based immunohistochemical study , European Journal of Histochemistry: Vol. 56 No. 3 (2012)
- A. Vetuschi, A. D'Alfonso, R. Sferra, D. Zanelli, S. Pompili, F. Patacchiola, E. Gaudio, G. Carta, Changes in muscularis propria of anterior vaginal wall in women with pelvic organ prolapse , European Journal of Histochemistry: Vol. 60 No. 1 (2016)
- Flavia Carton, Mathieu Repellin, Giovanna Lollo, Manuela Malatesta, Alcian blue staining to track the intracellular fate of hyaluronic-acid-based nanoparticles at transmission electron microscopy , European Journal of Histochemistry: Vol. 63 No. 4 (2019)
- Gong Cheng, Fengmin An, Zhilin Cao, Mingdi Zheng, Zhongyuan Zhao, Hao Wu, DPY30 promotes the growth and survival of osteosarcoma cell by regulating the PI3K/AKT signal pathway , European Journal of Histochemistry: Vol. 67 No. 1 (2023)
- A Chionna, E Panzarini, P Pagliara, A De Luca, S Caforio, L Abbro, L Dini, Hepatic clearance of apoptotic lymphocytes: simply removal of waste cells? , European Journal of Histochemistry: Vol. 47 No. 2 (2003)
- D Russo, A Ambrosino, A Vittoria, A Cecio, Signal amplification by combining two advanced immunohistochemical techniques , European Journal of Histochemistry: Vol. 47 No. 4 (2003)
- B Vitolo, MR Lidonnici, C Montecucco, A Montecucco, A new monoclonal antibody against DNA ligase I is a suitable marker of cell proliferation in cultured cell and tissue section samples , European Journal of Histochemistry: Vol. 49 No. 4 (2005)
<< < 44 45 46 47 48 49 50 51 52 53 > >>
You may also start an advanced similarity search for this article.
