https://doi.org/10.4081/ejh.2017.2851
DNA damage in acute myeloid leukemia patients of Northern Mexico
Submitted: 14 September 2017
Accepted: 30 November 2017
Published: 11 December 2017
Accepted: 30 November 2017
Abstract Views: 1030
PDF: 450
HTML: 129
HTML: 129
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
The purpose of this study was to evaluate DNA damage in the whole genome of peripheral blood leukocytes from patients with acute myeloid leukemia (AML) compared with a control group using DNA breakage detection-fluorescent in situ hybridization (DBD-FISH). Our results suggest that the DNA damage detected in patients with newly diagnosed AML was similar to that observed for the controls; this might be explained by the stimulation of a repair pathway by the pathogenesis itself. These findings indicate that inhibiting the repair pathway could be proposed to enhance the efficacy of chemotherapy.
Supporting Agencies
Instituto Mexicano del Seguro Social, CONACYT.How to Cite
Dávila-Rodríguez, M. I., Cortés-Gutiérrez, E. I., Hernández-Valdés, R., Guzmán-Cortés, K., De León-Cantú, R. E., Cerda-Flores, R. M., & Báez-De la Fuente, E. (2017). DNA damage in acute myeloid leukemia patients of Northern Mexico. European Journal of Histochemistry, 61(4). https://doi.org/10.4081/ejh.2017.2851
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Similar Articles
- J. Pelz, W. Härtig, C. Weise, C. Hobohm, D. Schneider, M. Krueger, J. Kacza, D. Michalski, Endothelial barrier antigen-immunoreactivity is conversely associated with blood-brain barrier dysfunction after embolic stroke in rats , European Journal of Histochemistry: Vol. 57 No. 4 (2013)
- Federico Angelo Cazzaniga, Edoardo Bistaffa, Chiara Maria Giulia De Luca, Giuseppe Bufano, Antonio Indaco, Giorgio Giaccone, Fabio Moda, Sporadic Creutzfeldt-Jakob disease: Real-Time Quaking Induced Conversion (RT-QuIC) assay represents a major diagnostic advance , European Journal of Histochemistry: Vol. 65 No. s1 (2021): Special Collection on Advances in Neuromorphology in Health and Disease
- L. Benerini Gatta, M. Cadei, P. Balzarini, S. Castriciano, R. Paroni, A. Verzeletti, V. Cortellini, F. De Ferrari, P. Grigolato, Application of alternative fixatives to formalin in diagnostic pathology , European Journal of Histochemistry: Vol. 56 No. 2 (2012)
- Silvia Damiana Visonà, Donatella Benati, Maria Cristina Monti, Mirco Galiè, Luisa Andrello, Andrea Frontini, Antonio Osculati, Diagnosis of sudden cardiac death due to early myocardial ischemia: An ultrastructural and immunohistochemical study , European Journal of Histochemistry: Vol. 62 No. 2 (2018)
- C. Pellicciari, Histochemistry through the years, browsing a long-established journal: novelties in traditional subjects , European Journal of Histochemistry: Vol. 54 No. 4 (2010)
- G. Laguna Hernández, A.E. Brechú-Franco, I. De la Cruz-Chacón, A.R. González-Esquinca, Histochemical detection of acetogenins and storage molecules in the endosperm of Annona macroprophyllata Donn Sm. seeds , European Journal of Histochemistry: Vol. 59 No. 3 (2015)
- M. Malatesta, M. Giagnacovo, M. Costanzo, B. Conti, I. Genta, R. Dorati, V. Galimberti, M. Biggiogera, C. Zancanaro, Diaminobenzidine photoconversion is a suitable tool for tracking the intracellular location of fluorescently labelled nanoparticles at transmission electron microscopy , European Journal of Histochemistry: Vol. 56 No. 2 (2012)
- Carlo Pellicciari, Is there still room for novelty, in histochemical papers? , European Journal of Histochemistry: Vol. 60 No. 4 (2016)
- Zhen Wang, Xiaoyan Du, Daoyang Yu, Yang Yang, Gaoen Ma, Xueli Jia, Lulu Cheng, Sufentanil alleviates cerebral ischemia-reperfusion injury by inhibiting inflammation and protecting the blood-brain barrier in rats , European Journal of Histochemistry: Vol. 66 No. 1 (2022)
- M.I. Dávila-RodrÃguez, Elva I. Cortés-Gutiérrez, R.M. Cerda Flores, M. Pita, J.L. Fernández, C. López-Fernández, J. Gosálvez, Constitutive heterochromatin polymorphisms in human chromosomes identified by whole comparative genomic hybridization , European Journal of Histochemistry: Vol. 55 No. 3 (2011)
<< < 3 4 5 6 7 8 9 10 11 12 > >>
You may also start an advanced similarity search for this article.
