Brief Reports
18 May 2018
6
2
4
0
Smart Citations
6
2
4
0
Citing PublicationsSupportingMentioningContrasting
View Citations

See how this article has been cited at scite.ai

scite shows how a scientific paper has been cited by providing the context of the citation, a classification describing whether it supports, mentions, or contrasts the cited claim, and a label indicating in which section the citation was made.

Appearance of β-dystroglycan precedes the formation of glio-vascular end-feet in developing rat brain

Authors

Dystroglycan has an important role in binding of perivascular glial end-feet tothe basal lamina. Its β-subunit is localized in the glial end-feet. The investigation period lasted from E(embryonic day)12 to E20. Laminin and β-dystroglycan were detected by immunohistochemistry, the glial localization of the latter one was supported  by electron microscopy. The immatureglial structures were visualized by the immunostaining of nestin. The β-dystroglycan immunoreactivity appeared at E16 following the laminin of basal lamina but preceding the perivascular processes of radial glia (E18) and astrocyte-like cells (E20). It occurred in cell bodies which attached to the vessels directly but not with vascular processes and end-feet. The presence of β-dystroglycan in such immature cells may promote their differentiation to perivascular astrocytes and influence the formation of the glio-vascular processes.

Altmetrics

Downloads

Citations

Supporting Agencies

Semmelweis University

How to Cite



Appearance of β-dystroglycan precedes the formation of glio-vascular end-feet in developing rat brain. (2018). European Journal of Histochemistry, 62(2). https://doi.org/10.4081/ejh.2018.2908