https://doi.org/10.4081/ejh.2018.2931
GalNAc-T15 in gastric adenocarcinoma: Characterization according to tissue architecture and cellular location
Accepted: 4 June 2018
Supplementary: 186
HTML: 15
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Gastric cancer (GC) is the second most common cause of cancer-related deaths in the world. This study aims to investigate the differential tissue expression of ppGalNAc-T15 and to evaluate its possible association with clinical-pathological parameters and outcome of gastric adenocarcinoma patients. For these 70 patients were evaluated the expression by immunohistochemistry to ppGalNAc-T15. Our results showed that 33 (47.1%) patients were ppGalNAC-T15+ positive and 37 (52.9%) negative. Positive staining for ppGalNAc-T15 was significantly present in patients older than 60 years (P=0.0306) and submitted to total gastrectomy (P=0.0087). Also, some results remained at the limit of significance as surgical standing (P=0.0562) and histological grade (P=0.0549). Therefore, the ppGalNAc-T15 immunoreactivity can be useful to understand the prognosis of patients with gastric cancer.
Supporting Agencies
CNPq, CAPES and FACEPEHow to Cite
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Similar Articles
- A.C. Croce, G. Bottiroli, Autofluorescence spectroscopy and imaging: a tool for biomedical research and diagnosis , European Journal of Histochemistry: Vol. 58 No. 4 (2014)
- Lisa Marie Wadephul, Kathrin Arndts, Gnatoulma Katawa, Eva Dietlmeier, William Horsnell, Achim Hoerauf, Manuel Ritter, Walking a thin line between fixation and epitope binding – characterization of antigen retrieval methods suitable for eosinophil and HSV-2 staining in formalin-fixed female reproductive tissue , European Journal of Histochemistry: Vol. 68 No. 2 (2024)
- Xiaoyan Chu, Jun Lou, Yun Yi, Linlin Zhong, Ouping Huang, Knockdown of ARHGAP30 inhibits ovarian cancer cell proliferation, migration, and invasiveness by suppressing the PI3K/AKT/mTOR signaling pathway , European Journal of Histochemistry: Vol. 67 No. 2 (2023)
- Cristina Maxia, Daniela Murtas, Michela Corrias, Ignazio Zucca, Luigi Minerba, Franca Piras, Cristiana Marinelli, Maria Teresa Perra, Vitamin D and vitamin D receptor in patients with ophthalmic pterygium , European Journal of Histochemistry: Vol. 61 No. 4 (2017)
- T. Karaca, Y. Hulya Uz, R. Karabacak, I. Karaboga, S. Demirtas, A. Cagatay Cicek, Effects of hyperthyroidism on expression of vascular endothelial growth factor (VEGF) and apoptosis in fetal adrenal glands , European Journal of Histochemistry: Vol. 59 No. 4 (2015)
- E. Varricchio, M.G. Russolillo, L. Maruccio, S. Velotto, G. Campanile, M. Paolucci, F. Russo, Immunological detection of m- and µ-calpains in the skeletal muscle of Marchigiana cattle , European Journal of Histochemistry: Vol. 57 No. 1 (2013)
- Yao Le, Zhijun Wang, Qian Zhang, Ling Miao, Xiaohong Wang, Guorong Han, Study on the mechanism of Shenling Baizhu powder on the pathogenesis of pregnancy complicated with non-alcoholic fatty liver, based on PI3K/AKT/mTOR signal pathway , European Journal of Histochemistry: Vol. 68 No. 3 (2024)
- L.O. Carvalho de Moraes, R.C. Tedesco, L.A. Arraez-Aybar, O. Klein, J.R. Mérida-Velasco, L.G. Alonso, Development of synovial membrane in the temporomandibular joint of the human fetus , European Journal of Histochemistry: Vol. 59 No. 4 (2015)
- R. M. Ruggeri, E. Vitarelli, G. Barresi, F. Trimarchi, S. Benvenga, M. Trovato, The tyrosine kinase receptor c-met, its cognate ligand HGF and the tyrosine kinase receptor trasducers STAT3, PI3K and RHO in thyroid nodules associated with Hashimoto's thyroiditis: an immunohistochemical characterization , European Journal of Histochemistry: Vol. 54 No. 2 (2010)
- K. Fujikawa, T. Yokohama-Tamaki, T. Morita, O. Baba, C. Qin, S. Shibata, An in situ hybridization study of perlecan, DMP1, and MEPE in developing condylar cartilage of the fetal mouse mandible and limb bud cartilage , European Journal of Histochemistry: Vol. 59 No. 3 (2015)
<< < 14 15 16 17 18 19 20 21 22 23 > >>
You may also start an advanced similarity search for this article.
