https://doi.org/10.4081/ejh.2018.2931
GalNAc-T15 in gastric adenocarcinoma: Characterization according to tissue architecture and cellular location
Accepted: 4 June 2018
Supplementary: 186
HTML: 15
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Gastric cancer (GC) is the second most common cause of cancer-related deaths in the world. This study aims to investigate the differential tissue expression of ppGalNAc-T15 and to evaluate its possible association with clinical-pathological parameters and outcome of gastric adenocarcinoma patients. For these 70 patients were evaluated the expression by immunohistochemistry to ppGalNAc-T15. Our results showed that 33 (47.1%) patients were ppGalNAC-T15+ positive and 37 (52.9%) negative. Positive staining for ppGalNAc-T15 was significantly present in patients older than 60 years (P=0.0306) and submitted to total gastrectomy (P=0.0087). Also, some results remained at the limit of significance as surgical standing (P=0.0562) and histological grade (P=0.0549). Therefore, the ppGalNAc-T15 immunoreactivity can be useful to understand the prognosis of patients with gastric cancer.
Supporting Agencies
CNPq, CAPES and FACEPEHow to Cite
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Similar Articles
- C. Loreto, A. Psaila, G. Musumeci, S. Castorina, R. Leonardi, Apoptosis activation in human carious dentin. An immunohistochemical study , European Journal of Histochemistry: Vol. 59 No. 3 (2015)
- Andrea Conz, Clara Alice Musi, Luca Russo, Tiziana Borsello, Luca Colnaghi, Super-resolution study of PIAS SUMO E3-ligases in hippocampal and cortical neurons , European Journal of Histochemistry: Vol. 65 No. s1 (2021): Special Collection on Advances in Neuromorphology in Health and Disease
- Antonella Vetuschi, Simona Pompili, Gian Piero Di Marco, Federico Calvaruso, Enzo Iacomino, Lidia Angelosante, Claudio Festuccia, Alessandro Colapietro, Roberta Sferra, Can the AGE/RAGE/ERK signalling pathway and the epithelial-to-mesenchymal transition interact in the pathogenesis of chronic rhinosinusitis with nasal polyps? , European Journal of Histochemistry: Vol. 64 No. 1 (2020)
- Federico Boschi, Francesco De Sanctis, Overview of the optical properties of fluorescent nanoparticles for optical imaging , European Journal of Histochemistry: Vol. 61 No. 3 (2017)
- L. Wang, J. Wang, X. Zhou, J. Li, Y. Shi, Z. Han, X. Wang, S. Li, Z. Yang, R. Wang, D. Fan, Y. Han, CM2 antigen, a potential novel molecule participating in glucuronide transport on rat hepatocyte canalicular membrane , European Journal of Histochemistry: Vol. 56 No. 3 (2012)
- A. Sbarbati, D. Accorsi, D. Benati, L. Marchetti, G. Orsini, G. Rigotti, P. Panettiere, Subcutaneous adipose tissue classification , European Journal of Histochemistry: Vol. 54 No. 4 (2010)
- M.A. Khalili, M. Maione, M.G. Palmerini, S. Bianchi, G. Macchiarelli, S.A. Nottola, Ultrastructure of human mature oocytes after vitrification , European Journal of Histochemistry: Vol. 56 No. 3 (2012)
- C. Serradifalco, P. Catanese, L. Rizzuto, F. Cappello, R. Puleio, V. Barresi, C. M. Nunnari, G. Zummo, V. Di Felice, Embryonic and foetal Islet-1 positive cells in human hearts are also positive to c-Kit , European Journal of Histochemistry: Vol. 55 No. 4 (2011)
- Huyi Liu, Xiangdao Cai , Jia Liu, Fengxiang Zhang , Andong He, Ruiman Li, The lncRNA MEG3 promotes trophoblastic cell growth and invasiveness in preeclampsia by acting as a sponge for miR-21, which regulates BMPR2 levels , European Journal of Histochemistry: Vol. 65 No. 4 (2021)
- M. Scimeca, A. Pietroiusti, F. Milano, L. Anemona, A. Orlandi, L.T. Marsella, E. Bonanno, Elemental analysis of histological specimens: a method to unmask nano asbestos fibers , European Journal of Histochemistry: Vol. 60 No. 1 (2016)
<< < 29 30 31 32 33 34 35 36 37 38 > >>
You may also start an advanced similarity search for this article.
