https://doi.org/10.4081/ejh.2018.2931
GalNAc-T15 in gastric adenocarcinoma: Characterization according to tissue architecture and cellular location
Accepted: 4 June 2018
Supplementary: 186
HTML: 15
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Gastric cancer (GC) is the second most common cause of cancer-related deaths in the world. This study aims to investigate the differential tissue expression of ppGalNAc-T15 and to evaluate its possible association with clinical-pathological parameters and outcome of gastric adenocarcinoma patients. For these 70 patients were evaluated the expression by immunohistochemistry to ppGalNAc-T15. Our results showed that 33 (47.1%) patients were ppGalNAC-T15+ positive and 37 (52.9%) negative. Positive staining for ppGalNAc-T15 was significantly present in patients older than 60 years (P=0.0306) and submitted to total gastrectomy (P=0.0087). Also, some results remained at the limit of significance as surgical standing (P=0.0562) and histological grade (P=0.0549). Therefore, the ppGalNAc-T15 immunoreactivity can be useful to understand the prognosis of patients with gastric cancer.
Supporting Agencies
CNPq, CAPES and FACEPEHow to Cite
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Similar Articles
- L Maccatrozzo, M Patruno, L Toniolo, C Reggiani, F Mascarello, Myosin Heavy Chain 2B isoform is expressed in specialized eye muscles but not in trunk and limb muscles of cattle , European Journal of Histochemistry: Vol. 48 No. 4 (2004)
- A Franchini, The distribution of cells containing FMRFamide- and 5-HT-related molecules in the embryonic development of Viviparus ater (Mollusca, Gastropoda) , European Journal of Histochemistry: Vol. 49 No. 3 (2005)
- K Smetana, Structural features of nucleoli in blood, leukemic, lymphoma and myeloma cells , European Journal of Histochemistry: Vol. 46 No. 2 (2002)
- Roberto Imberti, Alessandro Amatu, Drug delivery to the central nervous system , European Journal of Histochemistry: Vol. 54 No. 3 (2010)
- A. Amaroli, M.G. Chessa, Detection and characterisation of NAD(P)H-diaphorase activity in Dictyostelium discoideum cells (Protozoa) , European Journal of Histochemistry: Vol. 56 No. 4 (2012)
- Sergio Barni, In memoriam of Prof. Giuseppe Gerzeli , European Journal of Histochemistry: Vol. 62 No. 1 (2018)
- Claudio Pigoli, Lucia Rita Gibelli, Mario Caniatti, Luca Moretti, Giuseppe Sironi, Chiara Giudice, Bleaching melanin in formalin-fixed and paraffin-embedded melanoma specimens using visible light: a pilot study , European Journal of Histochemistry: Vol. 63 No. 4 (2019)
- Laura Calderan, Manuela Malatesta, Imaging techniques in nanomedical research , European Journal of Histochemistry: Vol. 64 No. 3 (2020)
- Manuela Monti, Perinatal Stem Cells - Biology, Manufacturing and Translational Medicine , European Journal of Histochemistry: Vol. 65 No. 3 (2021)
- E Muñoz, F Gómez, JI Paz, I Casado, Ki-67 immunolabeling in pre-malignant lesions and carcinoma of the prostate. Histological correlation and prognostic evaluation , European Journal of Histochemistry: Vol. 47 No. 2 (2003)
<< < 56 57 58 59 60 61 62 63 64 65 > >>
You may also start an advanced similarity search for this article.
