https://doi.org/10.4081/ejh.2018.2931
GalNAc-T15 in gastric adenocarcinoma: Characterization according to tissue architecture and cellular location
Accepted: 4 June 2018
Supplementary: 186
HTML: 15
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Gastric cancer (GC) is the second most common cause of cancer-related deaths in the world. This study aims to investigate the differential tissue expression of ppGalNAc-T15 and to evaluate its possible association with clinical-pathological parameters and outcome of gastric adenocarcinoma patients. For these 70 patients were evaluated the expression by immunohistochemistry to ppGalNAc-T15. Our results showed that 33 (47.1%) patients were ppGalNAC-T15+ positive and 37 (52.9%) negative. Positive staining for ppGalNAc-T15 was significantly present in patients older than 60 years (P=0.0306) and submitted to total gastrectomy (P=0.0087). Also, some results remained at the limit of significance as surgical standing (P=0.0562) and histological grade (P=0.0549). Therefore, the ppGalNAc-T15 immunoreactivity can be useful to understand the prognosis of patients with gastric cancer.
Supporting Agencies
CNPq, CAPES and FACEPEHow to Cite
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Similar Articles
- Christian Zuppinger, George Gibbons, Priyanka Dutta-Passecker, Adrian Segiser, Henriette Most, Thomas M. Suter, Characterization of cytoskeleton features and maturation status of cultured human iPSC-derived cardiomyocytes , European Journal of Histochemistry: Vol. 61 No. 2 (2017)
- Mariko Kawai, Yohei Kataoka, Junya Sonobe, Hiromitsu Yamamoto, Hiroki Maruyama, Toshio Yamamoto, Kazuhisa Bessho, Kiyoshi Ohura, Analysis of mineral apposition rates during alveolar bone regeneration over three weeks following transfer of BMP-2/7 gene via in vivo electroporation , European Journal of Histochemistry: Vol. 62 No. 3 (2018)
- Jianyu Zou, Zhenbin Cai, Zhi Liang , Yaozhong Liang, Guowei Zhang, Jie Yang, Yunlong Zhang, Hongsheng Lin, Minghui Tan, Different fusion tags affect the activity of ubiquitin overexpression on spastin protein stability , European Journal of Histochemistry: Vol. 65 No. 4 (2021)
- M.G. Manfredi Romanini, Postgenomic histochemistry , European Journal of Histochemistry: Vol. 47 No. 1 (2003)
- S Fakan, Ultrastructural cytochemical analyses of nuclear functional architecture , European Journal of Histochemistry: Vol. 48 No. 1 (2004)
- C Piñuela, C Rendón, ML González de Canales, C Sarasquete, Development of the Senegal sole, Solea senegalensis forebrain , European Journal of Histochemistry: Vol. 48 No. 4 (2004)
- S Ferrando, T Ferrando, L Girosi, A Mauceri, S Fasulo, G Tagliafierro, Apoptosis, cell proliferation and serotonin immunoreactivity in gut of Liza aurata from natural heavy metal polluted environments: preliminary observations , European Journal of Histochemistry: Vol. 49 No. 4 (2005)
- Ernesto Capanna, CarloAlberto Redi, Giving bodies to ghosts: locating molecules in the very place where they exert their biological roles , European Journal of Histochemistry: Vol. 68 No. 1 (2024): 1954-2024: 70 Years of Histochemical Research
- G Abban, NB Yildirim, AM Jetten, Regulation of the vitamin D receptor and cornifin beta expression in vaginal epithelium of the rats through vitamin D3 , European Journal of Histochemistry: Vol. 52 No. 2 (2008)
- CarloAlberto Redi, Apoptosis - Methods and Protocols , European Journal of Histochemistry: Vol. 54 No. 1 (2010)
<< < 62 63 64 65 66 67 68 69 > >>
You may also start an advanced similarity search for this article.
