https://doi.org/10.4081/ejh.2018.2969
Low ozone concentrations promote adipogenesis in human adipose-derived adult stem cells
Accepted: 13 August 2018
Supplementary: 0
HTML: 33
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Ozone is a strong oxidant, highly unstable atmospheric gas. Its medical use at low concentrations has been progressively increasing as an alternative/adjuvant treatment for several diseases. In this study, we investigated the effects of mild ozonisation on human adipose-derived adult stem (hADAS) cells i.e., mesenchymal stem cells occurring in the stromal-vascular fraction of the fat tissue and involved in the tissue regeneration processes. hADAS cells were induced to differentiate into the adipoblastic lineage, and the effect of low ozone concentrations on the adipogenic process was studied by combining histochemical, morphometric and ultrastructural analyses. Our results demonstrate that ozone treatment promotes lipid accumulation in hADAS without inducing deleterious effects, thus paving the way to future studies aimed at elucidating the effect of mild ozonisation on adipose tissue for tissue regeneration and engineering.
Supporting Agencies
University of VeronaHow to Cite
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Similar Articles
- M.A. Khalili, M. Maione, M.G. Palmerini, S. Bianchi, G. Macchiarelli, S.A. Nottola, Ultrastructure of human mature oocytes after vitrification , European Journal of Histochemistry: Vol. 56 No. 3 (2012)
- B Rovati, S Mariucci, M Manzoni, K Bencardino, M Danova, Flow cytometric detection of circulating dendritic cells in healthy subjects , European Journal of Histochemistry: Vol. 52 No. 1 (2008)
- D.G.B. Araújo, L. Nakao, P. Gozzo, C.D.A. Souza, V. Balderrama, E.S. Gugelmin, A.P. Kuczynski, M. Olandoski, L. de Noronha, Expression level of quiescin sulfhydryl oxidase 1 (QSOX1) in neuroblastomas , European Journal of Histochemistry: Vol. 58 No. 1 (2014)
- F. Dorko, D. Kluchová, A. Boleková, K. Lovasová, T. Špakovská, T. Borošová, Influence of surgical and chemical orchidectomy on weight and distribution of AChE-nerve fibres in thymuses of adult rats , European Journal of Histochemistry: Vol. 55 No. 3 (2011)
- S. Shibata, Y. Sakamoto, O. Baba, C. Qin, G. Murakami, B.H. Cho, An immunohistochemical study of matrix proteins in the craniofacial cartilage in midterm human fetuses , European Journal of Histochemistry: Vol. 57 No. 4 (2013)
- Roman M. Kassa, Roberta Bonafede, Federico Boschi, Manuela Malatesta, Raffaella Mariotti, The role of mutated SOD1 gene in synaptic stripping and MHC class I expression following nerve axotomy in ALS murine model , European Journal of Histochemistry: Vol. 62 No. 2 (2018)
- A. Di Giancamillo, M.E. Andreis, P. Taini, M.C. Veronesi, M. Di Giancamillo, S.C. Modina, Cartilage canals in newborn dogs: histochemical and immunohistochemical findings , European Journal of Histochemistry: Vol. 60 No. 3 (2016)
- Manxiu Cao, Lei Zhang, Jiaqi Chen, Cangyu Wang, Junhong Zhao, Xiang Liu, Yongjing Yan, Yue Tang, Zixiu Chen, Haihong Li, Differential antigen expression between human apocrine sweat glands and eccrine sweat glands , European Journal of Histochemistry: Vol. 67 No. 1 (2023)
- Rosa Manca, Chester Glomski , Alessandra Pica, Hematopoietic stem cells debut in embryonic lymphomyeloid tissues of elasmobranchs , European Journal of Histochemistry: Vol. 63 No. 3 (2019)
- Jianbao Yuan, Linfang Li, Yi Fan, Xinyu Xu, Xiaoqiong Huang, Jiayu Shi, Chuanwei Zhang, Lixin Shi, Yuliang Wang, Effects of artificial light with different spectral compositions on refractive development and matrix metalloproteinase 2 and tissue inhibitor of metalloproteinases 2 expression in the sclerae of juvenile guinea pigs , European Journal of Histochemistry: Vol. 68 No. 3 (2024)
<< < 45 46 47 48 49 50 51 52 53 54 > >>
You may also start an advanced similarity search for this article.
