https://doi.org/10.4081/ejh.2018.2969
Low ozone concentrations promote adipogenesis in human adipose-derived adult stem cells
Accepted: 13 August 2018
Supplementary: 0
HTML: 33
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Ozone is a strong oxidant, highly unstable atmospheric gas. Its medical use at low concentrations has been progressively increasing as an alternative/adjuvant treatment for several diseases. In this study, we investigated the effects of mild ozonisation on human adipose-derived adult stem (hADAS) cells i.e., mesenchymal stem cells occurring in the stromal-vascular fraction of the fat tissue and involved in the tissue regeneration processes. hADAS cells were induced to differentiate into the adipoblastic lineage, and the effect of low ozone concentrations on the adipogenic process was studied by combining histochemical, morphometric and ultrastructural analyses. Our results demonstrate that ozone treatment promotes lipid accumulation in hADAS without inducing deleterious effects, thus paving the way to future studies aimed at elucidating the effect of mild ozonisation on adipose tissue for tissue regeneration and engineering.
Supporting Agencies
University of VeronaHow to Cite
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Similar Articles
- C. Loreto, C. Galanti, G. Musumeci, M. C. Rusu, R. Leonardi, Immunohistochemical analysis of matrix metalloproteinase-13 in human caries dentin , European Journal of Histochemistry: Vol. 58 No. 1 (2014)
- F. Zhang, J. Wang, Y. Jiao, L. Zhang, H. Zhang, X. Sheng, Y. Han, Z. Yuan, Q. Weng, Seasonal changes of androgen receptor, estrogen receptors and aromatase expression in the medial preoptic area of the wild male ground squirrels (Citellus dauricus Brandt) , European Journal of Histochemistry: Vol. 60 No. 2 (2016)
- Federico Boschi, Francesco De Sanctis, Overview of the optical properties of fluorescent nanoparticles for optical imaging , European Journal of Histochemistry: Vol. 61 No. 3 (2017)
- A.E. Brechú-Franco, G. Laguna-Hernández, I. De la Cruz-Chacón, A.R. González-Esquinca, In situ histochemical localisation of alkaloids and acetogenins in the endosperm and embryonic axis of Annona macroprophyllata Donn. Sm. seeds during germination , European Journal of Histochemistry: Vol. 60 No. 1 (2016)
- S Burattini, P Ferri, M Battistelli, R Curci, F Luchetti, E Falcieri, C2C12 murine myoblasts as a model of skeletal muscle development: morpho-functional characterization , European Journal of Histochemistry: Vol. 48 No. 3 (2004)
- A Spano, L Sciola, G Monaco, S Barni, Relationship between actin microfilaments and plasma membrane changes during apoptosis of neoplastic cell lines in different culture conditions , European Journal of Histochemistry: Vol. 44 No. 3 (2000)
- E Bonanno, G Tagliafierro, EC Carlà, MR Montinari, P Pagliara, G Mascetti, LG Spagnoli, L Dini, Synchronized onset of nuclear and cell surface modifications in U937 cells during apoptosis , European Journal of Histochemistry: Vol. 46 No. 1 (2002)
- G D'Ancona Lunetta, ML Michelucci, Engagement of the periesophageal ring during Holothuria polii response to erythrocyte injection , European Journal of Histochemistry: Vol. 46 No. 2 (2002)
- A Chionna, M Dwikat, E Panzarini, B Tenuzzo, EC Carlà , T Verri, P Pagliara, L Abbro, L Dini, Cell shape and plasma membrane alterations after static magnetic fields exposure , European Journal of Histochemistry: Vol. 47 No. 4 (2003)
- Carlo Alberto Redi, Transgenic mouse - Methods and protocols, 2nd edition , European Journal of Histochemistry: Vol. 55 No. 3 (2011)
<< < 51 52 53 54 55 56 57 58 59 60 > >>
You may also start an advanced similarity search for this article.
