https://doi.org/10.4081/ejh.2020.3143
Prognostic significance of CD133 and ABCB5 expression in papillary thyroid carcinoma
Accepted: 3 November 2020
HTML: 4
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Expression of CD133 and ABCB5 is associated with tumor aggressiveness, but evidence in papillary thyroid cancer (PTC) is lacking. We correlated CD133 and ABCB5 expression with pathological characteristics and factors of worse prognosis in PTC. Samples of 119 PTCs and 40 controls (goiters) were distributed in 8 tissue microarray blocks and evaluated with immunohistochemistry using anti-CD133 and anti-ABCB5 antibodies. The expression of each marker alone and combined was analyzed against pathological characteristics and factors of worse prognosis in PTC. Expression of CD133 alone (19 tumors, 16.0%) was more frequent in patients with versus without lymph node metastases (P=0.024). Expression of ABCB5 alone (n=95, 83.3%) was associated with larger tumor size (P=0.045). CD133-ABCB5 coexpression was not associated with pathological characteristics or factors of worse prognosis in PTC.
Supporting Agencies
Mackenzie Evangelical College of Paraná (Curitiba, Paraná, Brazil), Coordenação de Aperfeiçoamento de Pessoal de Nível Superior – Brasil (CAPES)How to Cite
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Similar Articles
- Zhen Wang, Xiaoyan Du, Daoyang Yu, Yang Yang, Gaoen Ma, Xueli Jia, Lulu Cheng, Sufentanil alleviates cerebral ischemia-reperfusion injury by inhibiting inflammation and protecting the blood-brain barrier in rats , European Journal of Histochemistry: Vol. 66 No. 1 (2022)
- H. Huang, W. Wang, P. Liu, Y. Jiang, Y. Zhao, H. Wei, W. Niu, TRPC1 expression and distribution in rat hearts , European Journal of Histochemistry: Vol. 53 No. 4 (2009)
- Carlo Alberto Redi, RNA therapeutics - Function, design and delivery , European Journal of Histochemistry: Vol. 55 No. 2 (2011)
- M. Monti, In vivo cellular imaging using fluorescent proteins - Methods and Protocols , European Journal of Histochemistry: Vol. 56 No. 4 (2012)
- D. Rizo-Roca, J.G. RÃos-Kristjánsson, C. Núñez-Espinosa, A. Ascensão, J. Magalhães, J.R. Torrella, T. Pagès, G. Viscor, A semiquantitative scoring tool to evaluate eccentric exercise-induced muscle damage in trained rats , European Journal of Histochemistry: Vol. 59 No. 4 (2015)
- M Battistelli, R De Sanctis, R De Bellis, L Cucchiarini, M Dachà , P Gobbi, Rhodiola Rosea as antioxidant in red blood cells: ultrastructural and hemolytic behaviour , European Journal of Histochemistry: Vol. 49 No. 3 (2005)
- F Cappello, M Bellafiore, A Palma, S David, V Marcianò, T Bartolotta, C Sciumè, G Modica, F Farina, G Zummo, F Bucchieri, 60KDa chaperonin (HSP60) is over-expressed during colorectal carcinogenesis , European Journal of Histochemistry: Vol. 47 No. 2 (2003)
- B Bilinska, M Kotula-Balak, J Sadowska, Morphology and function of human Leydig cells in vitro. Immunocytochemical and radioimmunological analyses , European Journal of Histochemistry: Vol. 53 No. 1 (2009)
- A Alunni, S Vaccari, S Torcia, Characterization of glial fibrillary acidic protein and astroglial architecture in the brain of a continuously growing fish, the rainbow trout , European Journal of Histochemistry: Vol. 49 No. 2 (2005)
- H Ishida, M Kumakiri, K Ueda, LM Lao, M Yanagihara, K Asamoto, Y Imamura, S Noriki, M Fukuda, Comparative histochemical study of Bowen’s disease and actinic keratosis: preserved normal basal cells in Bowen’s disease , European Journal of Histochemistry: Vol. 45 No. 2 (2001)
<< < 50 51 52 53 54 55 56 57 58 59 > >>
You may also start an advanced similarity search for this article.
