The Feulgen reaction at the electron microscopy level

Submitted: 12 February 2024
Accepted: 14 February 2024
Published: 23 February 2024
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The Feulgen reaction has been the first specific method for detecting DNA available at light microscopy since 1924. However, a similar specific method was proposed for electron microscopy only 50 years later. Here, we discuss the problems encountered in finding the electrondense reagent capable of taking advantage of the extremely high resolution offered by electron microscopy as well as some applications of the method.

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How to Cite

Biggiogera, M. (2024). The Feulgen reaction at the electron microscopy level. European Journal of Histochemistry, 68(1). https://doi.org/10.4081/ejh.2024.3989

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