Original Papers
26 June 2009
Vol. 47 No. 1 (2003)
10
0
3
0
Smart Citations
10
0
3
0
Citing PublicationsSupportingMentioningContrasting
View Citations

See how this article has been cited at scite.ai

scite shows how a scientific paper has been cited by providing the context of the citation, a classification describing whether it supports, mentions, or contrasts the cited claim, and a label indicating in which section the citation was made.

Morphochemical age-related changes in the nematode Caenorhabditis elegans: immunoperoxidase localization of cytokine- and growth factor-like molecules

Authors

Morphochemical age-related features in the hermaphrodite Caenorhabditis elegans are reported. The study of worms of different ages shows a gradual decline in response to the various histochemical reactions and a disorganization of the components of the gonad during ageing. Using an immunocytochemical procedure, we show for the first time the presence of immunoreactive IL-1a and PDGF-AB molecules in neurons from young adult C. elegans. Moreover, TNF-a- and PDGF-AB-like molecules are also present in the secretory cells of the pharyngeal terminal bulb. The number of positive cells to anti-cytokine and anti-growth factor antibodies decreases in older worms, suggesting that these molecules may play an important role in worm ageing. The present investigation therefore supports the findings in the literature obtained with different approaches on the crucial role of the nervous and reproductive systems in the life span of C. elegans.

Altmetrics

Downloads

Citations

Crossref
8
Scopus
0
Crossref Logo
E. Ottaviani, D. Malagoli, A. Franchini (2003)
Invertebrate Cytokines and the Phylogeny of Immunity. Progress in Molecular and Subcellular Biology, 34, 1.
Crossref Logo
Antonella Franchini, Mauro Mandrioli, Claudio Franceschi, Enzo Ottaviani (2012)
Morpho-functional changes of fat body in bacteria fed Drosophila melanogaster strains. Journal of Molecular Histology, 43(2), 243.
Crossref Logo
A. Franchini, E. Ottaviani (2008)
Age-related toxic effects and recovery from okadaic acid treatment in Enchytraeus crypticus (Annelida: Oligochaeta). Toxicon, 52(1), 115.
Crossref Logo
Ilaria Negri, Antonella Franchini, Elena Gonella, Daniele Daffonchio, Peter John Mazzoglio, Mauro Mandrioli, Alberto Alma (2009)
Unravelling theWolbachiaevolutionary role: the reprogramming of the host genomic imprinting. Proceedings of the Royal Society B: Biological Sciences, 276(1666), 2485.
Crossref Logo
Janet E Alexander, Alison Colyer, Richard M Haydock, Michael G Hayek, JeanSoon Park (2018)
Understanding How Dogs Age: Longitudinal Analysis of Markers of Inflammation, Immune Function, and Oxidative Stress. The Journals of Gerontology: Series A, 73(6), 720.
Crossref Logo
Martin S. Staege, Stefanie Kewitz, Toralf Bernig, Caspar Kühnöl, Christine Mauz-Körholz (2015)
Prognostic Biomarkers for Hodgkin Lymphoma. Pediatric Hematology and Oncology, 32(7), 433.
Crossref Logo
Antonella Franchini, Carol Imbriano, Elisa Peruzzi, Roberto Mantovani, Enzo Ottaviani (2005)
Expression of the CCAAT-binding factor NF-Y in Caenorhabditis elegans. Journal of Molecular Histology, 36(1), 139.
Crossref Logo
A. Franchini, E. Ottaviani (2007)
IL-6 immunoreactivity changes during aging in the polychaete Ophryotrocha labronica (Polychaeta: Dorvilleidae). Tissue and Cell, 39(1), 27.

How to Cite



Morphochemical age-related changes in the nematode Caenorhabditis elegans: immunoperoxidase localization of cytokine- and growth factor-like molecules. (2009). European Journal of Histochemistry, 47(1), 75-80. https://doi.org/10.4081/809