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Presence of atrial natriuretic factor in normal and hyperplastic human prostate and its relationship with oxytocin localisation

Authors

E Farina-Lipari
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D Lipari
M Bellafiore
R Anzalone
F Cappello
B Valentino
In this work, we showed the presence of atrial natriuretic factor (ANF) in human prostate and compared its localisation in normal and hyperplastic conditions. ANF was localised in epithelial and stromal cells, being increased in hyperplasia, mainly in the stromal component. Moreover, we compared ANF and oxytocin positivity in the same glands, focusing on the possible relationship between the paracrine effects of these two hormones.

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10.1007/s00441-004-0968-5
M. L. Gould, H. D. Nicholson (2019)
Changes in receptor location affect the ability of oxytocin to stimulate proliferative growth in prostate epithelial cells. Reproduction, Fertility and Development, 31(6), 1166.
10.1071/RD18362
A. Mauro, M. Buscemi, F. Cappello, M. L. Uzzo, E. Farina‐Lipari, A. Martorana, A. Gerbino (2009)
Immunohistochemical and Biomolecular Identification of Orphanin FQ, eNOS, Atrial natriuretic Factor and Oxytocin in Rat Seminal Vesicles. Anatomia, Histologia, Embryologia, 38(6), 443.
10.1111/j.1439-0264.2009.00968.x
N. Mottet, Y. Chaussy, F. Arbez-Gindre, D. Riethmuller (2017)
Fisiología y patologías del cordón umbilical. EMC - Ginecología-Obstetricia, 53(4), 1.
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How to Cite

Farina-Lipari, E., Lipari, D., Bellafiore, M., Anzalone, R., Cappello, F., & Valentino, B. (2009). Presence of atrial natriuretic factor in normal and hyperplastic human prostate and its relationship with oxytocin localisation. European Journal of Histochemistry, 47(2), 133–138. https://doi.org/10.4081/818

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