https://doi.org/10.4081/963

Emerin increase in regenerating muscle fibers

Vol. 49 No. 4 (2005)
Published: 30 June 2009
Abstract Views: 564
PDF: 434
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Authors

S Squarzoni
support@pagepress.org
P Sabatelli
C Capanni
G Lattanzi
C Rutigliano
M Columbaro
The fate of emerin during skeletal muscle regeneration was investigated in an animal model by means of crush injury. Immunofluorescence, immunoblotting and mRNA analysis demonstrated that emerin level is increased in regenerating rat muscle fibers with respect to normal mature myofibers. This finding suggests an involvement of emerin during the muscle fiber regeneration process, in analogy with its reported involvement in muscle cell differentiation in vitro. The impairment of skeletal muscle physiological regeneration or reorganization could be a possible pathogenetic mechanism for Emery Dreifuss muscular dystrophy.

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How to Cite

Squarzoni, S., Sabatelli, P., Capanni, C., Lattanzi, G., Rutigliano, C., & Columbaro, M. (2009). Emerin increase in regenerating muscle fibers. European Journal of Histochemistry, 49(4), 355–362. https://doi.org/10.4081/963

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