Emerin increase in regenerating muscle fibers

S Squarzoni; P Sabatelli; C Capanni; G Lattanzi; C Rutigliano; M Columbaro

doi:10.4081/963

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S Squarzoni

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P Sabatelli

C Capanni

G Lattanzi

C Rutigliano

M Columbaro

The fate of emerin during skeletal muscle regeneration was investigated in an animal model by means of crush injury. Immunofluorescence, immunoblotting and mRNA analysis demonstrated that emerin level is increased in regenerating rat muscle fibers with respect to normal mature myofibers. This finding suggests an involvement of emerin during the muscle fiber regeneration process, in analogy with its reported involvement in muscle cell differentiation in vitro. The impairment of skeletal muscle physiological regeneration or reorganization could be a possible pathogenetic mechanism for Emery Dreifuss muscular dystrophy.

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Daria Camozzi, Cristina Capanni, Vittoria Cenni, Elisabetta Mattioli, Marta Columbaro, Stefano Squarzoni, Giovanna Lattanzi (2014)

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Structural and functional alterations of the cell nucleus in skeletal muscle wasting: The evidence in situ. European Journal of Histochemistry, 54(4), 197-199.
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How to Cite

Squarzoni, S., Sabatelli, P., Capanni, C., Lattanzi, G., Rutigliano, C., & Columbaro, M. (2009). Emerin increase in regenerating muscle fibers. European Journal of Histochemistry, 49(4), 355–362. https://doi.org/10.4081/963

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