https://doi.org/10.4081/998

Inmunohistochemical expression of p53, Bcl-2, COX-2, C-erb-B2, EPO-R, ?-catenin, and E-cadherin in non tumoral gastric mucous membrane

Vol. 50 No. 4 (2006)
Published: 30 June 2009
Abstract Views: 416
PDF: 355
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Authors

M Sereno
support@pagepress.org
MA García-Cabezas
J De Castro
P Cejas
E Casado Saenz
C Belda-Iniesta
J Barriuso Feijoo
J Larrauri
M Nistal
M Gonzalez Baron
Different authors have investigated the immunohistochemical expression of some proteins in the adenocarcinoma of the stomach, including cell cycle regulators proteins like p53 and Bcl-2; growth factors (c-erb-B2 and EPO-R); angiogenesis- related markers such as COX-2 and cellular adhesion molecules (?-catenin and E-cadherin). While these proteins have been studied in gastric adenocarcinoma, their immunophenotyping in non tumoral gastric mucous membrane remains unexplored. In the present study, we investigated the expression, function and behavior of these proteins in normal gastric mucous membrane to contribute to gain further knowledge on the significance of their loss or overexpression in malignant gastric tumors.

Dimensions

Altmetric

PlumX Metrics

Downloads

Download data is not yet available.

Citations

Crossref
Scopus
Google Scholar
Europe PMC

How to Cite

Sereno, M., García-Cabezas, M., De Castro, J., Cejas, P., Casado Saenz, E., Belda-Iniesta, C., … Gonzalez Baron, M. (2009). Inmunohistochemical expression of p53, Bcl-2, COX-2, C-erb-B2, EPO-R, ?-catenin, and E-cadherin in non tumoral gastric mucous membrane. European Journal of Histochemistry, 50(4), 285–292. https://doi.org/10.4081/998

PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.