Identification of the novel localization of tenascinX in the monkey choroid plexus and comparison with the mouse

Authors

Tenascin-X (Tn-X) belongs to the tenascin family of glycoproteins and has been reported to be significantly associated with schizophrenia in a single nucleotide polymorphism analysis in humans. This finding indicates an important role of Tn-X in the central nervous system (CNS). However, details of Tn-X localization are not clear in the primate CNS. Using immunohistochemical techniques, we found novel localizations of Tn-X in the interstitial connective tissue and around blood vessels in the choroid plexus (CP) in macaque monkeys. To verify the reliability of Tn-X localization, we compared the Tn-X localization with the tenascin-C (Tn-C) localization in corresponding regions using neighbouring sections. Localization of Tn-C was not observed in CP. This result indicated consistently restricted localization of Tn-X in CP. Comparative investigations using mouse tissues showed equivalent results. Our observations provide possible insight into specific roles of Tn-X in CP for mammalian CNS function.

Downloads

Publication Facts

Metric
This article
Other articles
Peer reviewers 
0
2.4

Reviewer profiles  N/A

Author statements

Author statements
This article
Other articles
Data availability 
N/A
16%
External funding 
N/A
32%
Competing interests 
N/A
11%
Metric
This journal
Other journals
Articles accepted 
57%
33%
Days to publication 
7
145

Indexed in

Editor & editorial board
profiles
Academic society 
N/A

PFL

1 2 3 4 5
Not useful Very useful

Citations

How to Cite

Imura, K., & Sato, I. (2009). Identification of the novel localization of tenascinX in the monkey choroid plexus and comparison with the mouse. European Journal of Histochemistry, 53(4), e27. https://doi.org/10.4081/ejh.2009.e27

Similar Articles

<< < 29 30 31 32 33 34 35 36 37 38 > >> 

You may also start an advanced similarity search for this article.