@article{Boniotto_Pirulli_Verga Falzacappa_Trevisiol_Gerarduzzi_Crovella_2009, title={Localization and expression of two human b-defensins (HBD-1 and HBD-2) in intestinal biopsies of celiac patients}, volume={47}, url={https://www.ejh.it/ejh/article/view/852}, DOI={10.4081/852}, abstractNote={Innate immunity is the first line of defense against microorganisms in vertebrates and acts by providing an initial barrier to microorganisms and triggering adaptive immune responses (Ganz and Lehrer 1999; Oppenheim et al., 2002). Peptides such as b-defensins are an important component of this defense, both providing a broad spectrum of antimicrobial activity against bacteria, fungi, mycobacteria and several enveloped viruses (Ganz and Leher, 1994) and showing chemotactic activity by linking and activating CCR6 (Hoover DM et al. , 2002). b-defensins are small cationic peptides that vary in their expression patterns and spectrum of pathogen specificity (Ganz and Leher, 2002).}, number={4}, journal={European Journal of Histochemistry}, author={Boniotto, M and Pirulli, D and Verga Falzacappa, MV and Trevisiol, C and Gerarduzzi, T and Crovella, S}, year={2009}, month={Jun.}, pages={389–392} }